程仲彬 男 理学博士  副教授  硕士生导师

1.教育背景

2017.09-2022.08  河南大学 伟德bv1946官网讲师、副教授

2014.09-2017.06 北京大学 生药学专业 博士

2011.09-2014.06 中山大学 生药学 硕士

2007.09-2011.06 中山大学 药学 学士  

2.教学情况

负责天然药物化学部分章节

3.科研情况

在Journal of Natural Products、Bioorganic Chemistry、Marine Drugs、Fitoterapia等期刊发表第一或通讯作者论文20余篇。主持国自然青年项目、博士后面上一等资助等项目。

4.研究领域

海洋真菌、海南药用植物活性成分研究

5.代表性项目

(1) 国家自然科学基金青年项目, 81903536, 深海土曲霉中a-葡萄糖苷酶抑制剂的发现、结构优化及构效关系研究, 2020/01-2022/12, 20万元，主持

(2) 中国博士后科学基金第63批面上一等资助，2018M630815，海洋真菌PD-E1的次生代谢产物及其抗食管癌活性研究，2018/01-2020/12, 8万元，主持

(3) 河南省青年托举工程项目，2020HYTP059，托姆青霉Penicillium thomii中色原酮类抗炎成分的发现及作用机制研究，2020/01-2022/12, 5万元，主持

6.代表性成果

[1] Q. Li, W. Xu, R. Fan, J. Zhang, Y. Li, X. Wang, S. Han, W. Liu, M. Pan, Z. Cheng*, Penithoketone and Penithochromones A–L, Polyketides from the deep-sea-derived fungus Penicillium thomii YPGA3, Journal of Natural Products 2020, 83, 2679–2685.

[2] Z. Cheng*, Y. Li, W. Xu, W. Liu, L. Liu, D. Zhu, Y. Kang, Z. Luo, Q. Li*,. Three new cyclopiane-type diterpenes from a deep-sea derived Penicillium sp. YPGA11 fungus and their effects against human esophageal carcinoma cells. Bioorganic Chemistry 2019, 91, 103129.

[3] Z. Cheng, W. Xu, L. Liu, S. Li, W. Yuan, Z. Luo, J. Zhang, Y. Cheng, Q. Li*,. Peniginsengins B–E, New farnesylcyclohexenones from the deep sea-derived fungus Penicillium sp. YPGA11. Marine Drugs 2018, 16, 358

[4] Z. Cheng, Y. Li, W. Liu, L. Liu, J. Liu, W. Yuan*, Z. Luo, W. Xu*, Q. Li*,. Butenolide derivatives with α-glucosidase inhibitions from the deep-sea-derived fungus Aspergillus terreus YPGA10. Marine Drugs 2019, 17, 332.

[5] Z. Cheng*, W. Liu, R. Fan, S. Han, Y. Li, X. Cui, J. Zhang, Y. Wu, X. Lv, Y. Zhang, Z. Luo, S.A. Alias, W. Xu*, Q. Li*, Terpenoids from the deep-sea-derived fungus Penicillium thomii YPGA3 and their bioactivities, Marine Drugs 2020, 18, 164.

[6] Z. Cheng, W. Xu, Y. Wang, S. Bai, L. Liu, Z. Luo, W. Yuan*, Q. Li*, Two new meroterpenoids and two new monoterpenoids from the deep sea-derived fungus Penicillium sp. YPGA11. Fitoterapia, 2019, 133, 120-124.

[7]Y. Li, W. Liu, S. Han, J. Zhang, W. Xu, Q. Li, Z. Cheng*, Penitholabene, a rare 19-nor labdane-type diterpenoid from the deep-sea-derived fungus Penicillium thomii YPGA3, Fitoterapia,2020, 146, 104691.

[8] Z. Cheng, L. Lou, D. Liu, X. Li, P. Proksch, S. Yin, W. Lin*. Versiquinazolines A-K, Fumiquinazoline-type alkaloids from the gorgonian-derived fungus Aspergillus versicolor LZD-14-1. Journal of Natural Products, 2016, 79, 2941-2952.

[9] Z. Cheng, J. Zhao, D. Liu, P. Proksch, Z. Zhao*, W. Lin*. Eremophilane-type sesquiterpenoids from an Acremonium sp. fungus isolated from deep-sea sediments. Journal of Natural Products 2016, 79, 1035-1047.

[10] Z.-B. Cheng, X. Lu, J.-M. Bao, Q.-H. Han, Z. Dong, G.-H. Tang, L.-S. Gan*, H.-B. Luo*, S. Yin*. (±)-Torreyunlignans A-D, rare 8-9¢ linked neolignan enantiomers as phosphodiesterase-9A inhibitors from Torreya yunnanensis. Journal of Natural Products, 2014, 77 (12), 2651-2657.

[11] Z.-B. Cheng, Y.L. Deng, C.Q. Fan, Q.H. Han, S.L. Lin, G.H. Tang, H.B. Luo*, S. Yin*. Prostaglandin derivatives: Nonaromatic phosphodiesterase-4 inhibitors from the soft coral Sarcophyton ehrenbergi. Journal of Natural Products, 2014, 77, 1928-1936.

[12] Z.B. Cheng, W.W. Shao, Y.N. Liu, Q. Liao, T.T. Lin, X.Y. Shen, S. Yin*. Extracellular signal-regulated kinases (ERK) inhibitors from Aristolochia yunnanensis. Journal of Natural Products, 2013, 76, 664-671.